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Licensed oral rehydration salts (ORS) available from pharmacies should be used as they contain the appropriate balance of glucose and electrolytes

Many patients see steady, sustainable reductions in body weight

Midlife inflammation is a key driver of weight gain, joint pain, brain fog and long-term cardiovascular risk, and is increasingly recognised as central to midlife metabolic health

Conflict of interest Aleksandra Biaczyk, Adam Weniak, Barbara Kamiska and Rafa Czajkowski have no conflicts of interest that are directly relevant to the content of this article

Certain skin-related symptoms during GLP-1 treatment require prompt medical attention

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