fda removes tirzepatide from shortage list says compounding pharmacies can keep making weight-loss med tirzepatide, for now FDA Removes Tirzepatide from Shortage

Patients taking GLP-1s may lose weight, improve glucose control, reduce cardiometabolic risk, and engage more intensively with health care

In patients with T2DM, where islet neogenesis and -cell replication are normal, increased apoptosis is the main cause of the decrease in their -cell numbers, so preventing -cell apoptosis may become an effective means of treating T2DM ( GLP-1 has a beneficial effect on -cell function by promoting -cell proliferation and neogenesis and reducing apoptosis (Zheng et al., 2022)

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Altogether, these proteins may contribute to modulating the metastatic potential of cancer cells [61,62]

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Thats because the dosing of the oral medication makes it relatively ineffective for weight loss