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Considering the fact that formation of many crystals usually is associated with tissue injury, more studies are needed to clarify the significance of Charcot-Leyden crystals released during EETosis [47]

Consequently, simulations suggest that while doxorubicin redox metabolism impacts GSH metabolism, the concentrations required to illicit a toxic response, with either a single or extended exposure, reside outside that of the therapeutic dosing range

Regarding the type of study conducted, 43% are cross-sectional, followed by randomized controlled trials (36%) and cohort studies (19%)

1, (eds Nord, F

doi: 10.3389/fphar.2020.00854 61 ShaheenS

Likewise, the overexpression of SOD is children with Down syndrome leads to a reduction of GSH and an increase in oxidative stress [13]