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Progress towards the discovery of xanthine oxidase inhibitors

J Chromatog 877B:33093317 James MO, Bowen ER, Dansette PM, Bend JR (1979) Epoxide hydrase and glutathione S -transferase activities with selected alkene and arene oxides in several marine species

Those with liver or kidney disease might need their doses changed because these conditions can affect how B12 is processed and removed from the body

Compared with the synthetic cyanocobalamin form found in many supplements, hydroxocobalamin retains in the body for longer and does not require the body to cleave off and excrete a cyanide molecule before use

We would not expect a close match to the clinically observed percentage changes because we are comparing intracellular model changes to blood measurements

Collectively, these findings indicate a metabolic shift from FAO to glycolysis in TECs during AKI