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Pharmacology Research: 5-Amino-1MQ serves as a lead compound in NNMT inhibitor drug development

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Griffiths RR, Johnson MW, Carducci MA, Umbricht A, Richards WA, Richards BD, et al

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In November 2023, the FDA granted approval for Zepbound (tirzepatide) for chronic weight management in adults with obesity (body mass index 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbid condition such as hypertension, dyslipidemia, type 2 diabetes, obstructive sleep apnea, or cardiovascular disease