Reality: In healthy individuals, the kidneys are designed to filter and eliminate watersoluble compounds
The correlation coefficient between the two protocols was 0.9967
One caveat that should also be noted is that many animal models involve relatively severe challenge conditions for example, direct cerebral injection of virus and so the extrapolation of any conclusions to natural exposure of humans should be treated with caution
You would need to draw twice, introducing additional error and contamination risk with each needle puncture
PubMed Central, Vincenti, Alessandra, et al
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