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TRPM8 contributes to liver regeneration via mitochondrial energy metabolism mediated by PGC1

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GIP looks a lot like GLP-1, so rather than administer two drugs, researchers created one peptide that incorporates structural elements of bothwhats called in drug development a chimera

The researchers aimed to investigate whether specific medications for diabetes and obesity (namely, GLP-1 receptor agonists, SGLT2 inhibitors, and DPP4 inhibitors) had an impact on their likelihood of experiencing pancreatitis again

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A 2023 study in the journal Diabetes, Obesity and Metabolism examined hormonal changes in men on semaglutide and found improvements in testosterone levels that were partially, but not entirely, explained by weight loss alone