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The research versus pharmaceutical grade comparison also matters here, because pharmaceutical-grade formulations often come pre-reconstituted at standardized concentrations, eliminating the calculation step entirely

We also assessed the neuronal pathological changes in acquired digital images saved as uncompressed 24-bit RGB TIFF files in the software program AnalySIS (Olympus Soft Imaging System GmbH, Munster, Germany) by performing quantitative analysis of the neuronal damage in the karyopyknotic areas

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doi:10.3390/ijms26062691 Gatta M, Dovizio M, Milillo C, et al