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This chronic inflammatory disease is characterized by an increase in M1 macrophages in the oral cavity, which disrupts the M1/M2 macrophage ratio, creating a hyperinflammatory environment [73]

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However, differences in sociodemographic profile and comorbidities were present, such as higher incomes and educational level of GLP-1 RAs users compared with SGLT-2 inhibitor users and DPP-4 inhibitor users suggesting selection bias in prescription

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For instance, losing weight on these medications doesnt only involve fat but other tissues like muscle, which can be problematic for older individuals already at risk for muscle loss, Almandoz and Oladunjoye said