Diabetes guidelines recommend these GLP-1 RAs as pharmacologic agents in patients with ASCVD or with high-risk indicators for cardiovascular disease
Clinical studies have shown that individuals using semaglutide experience substantial weight loss, often exceeding that achieved with other medications
At 40 weeks, mean body weight changes were 7.5 kg with 10 mg and 8.8 kg with 15 mg doses, compared to 1.6 kg with placebo
Diet & Exercise (Lifestyle Interventions): Pros: Safe, zero cost, vital for overall health
News articles abound about the fears around high prices for GLP-1s, and Senators are claiming the prices are unjustifiably high because of how many patients could benefit from them if they were cheaper
But berberine is still a reasonable option for some people looking for gentle, natural metabolic support, and that is a different goal from prescription weight loss