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Some physicians are willing to hold patients at lower doses if the side effects are tolerable and the clinical response is adequate

A SYBR Premix Ex Taq II (Tli RNaseH Plus) Kit was used to perform qRT-PCR in technical triplicate on a StepOnePlus Real-time PCR System (Applied Biosystems, USA) following the manufacturers instructions

Third, observational studies overstate correlationsserum EPA/DHA levels (63, 72) may be a marker of an overall healthy diet (e.g., high fish intake often coincides with high fiber and vitamin intake) rather than a direct driver of depression (62, 72)

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