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La ricerca preclinica ha rivelato un ampio spettro di attivit biologiche, tra cui la citoprotezione gastrica, la modulazione della via dell'ossido nitrico (NO) e l'interazione con il sistema dopaminergico

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Patent No.10,278,923 describes the use of GLP-1 peptides in oral therapy

J Exp Med 213:12231239

This weight rebound pattern was documented in multiple semaglutide withdrawal studies, where patients who paused treatment experienced appetite increases that often exceeded their pre-treatment baseline

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