When the body's tissues become less responsive to insulin, a condition known as insulin resistance, it increases the risk of type 2 diabetes mellitus (T2DM), metabolic syndrome, fatty liver disease, and atherosclerosis (Lee et al., 2022)
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Translating a nanomoles-per-kilogram dose into an absolute microgram amount requires only the molecular weight of 849 Daltons, but the precise per-kilogram microgram figure varies with body weight and the exact nanomole dose selected
The nasal route facilitates non-invasive administration, avoiding the need for injections or complex delivery systems, which may simplify protocol designs during experimental procedures
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While GLP-1 medications can offer important benefits to patients with diabetes and obesity, they also carry significant price tags
