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Selective NNMT inhibitors (including 5-Amino-1MQ) lower 1-MNA, increase NAD and SAM, suppress adipocyte lipogenesis, and reverse HFD-induced obesity in mice [1]

The ethical considerations surrounding performance enhancement versus legitimate medical treatment must be carefully considered, and healthcare providers should ensure that any use of these peptides in athletic populations is medically justified and compliant with applicable anti-doping regulations

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