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Ipamorelin triggers GH release, while CJC-1295 amplifies and extends the pituitarys GH-releasing signal

However, the combination therapy was associated with a higher occurrence of gastrointestinal issues like nausea, with rates ranging from 20% to 47%

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Faux NG, Ellis KA, Porter L, Fowler CJ, Laws SM, Martins RH, Pertile KK, Rembach A, Rowe CC, Rumble RL et al

The investigators reported improvements in skin density, dermal thickness, laxity (firmness), and reduction of fine lines in the GHK-Cu arm compared with vehicle control over the 12-week treatment period [3]

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