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Collagen and ECM Remodeling Maquart et al

Cardiovascular disease is another major driver

Patients with moderate renal insufficiency received 50 mg daily of JANUVIA and those with severe renal insufficiency or with ESRD on hemodialysis or peritoneal dialysis received 25 mg daily

Both approaches can be effective

A nasal spray is also available but is not considered the best treatment for severe deficiency because B12 is not absorbed as well as it is via injection

Drugs that don't cause impairment, don't have abuse potential, and aren't controlled substances are not candidates for standard screening regardless of how many people use them