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Newly developed, receptor-selective glutamate compounds are often hampered by the uncertain toxicity and the tolerability profile

GSH (-glutamyl-cysteinyl-glycine) is produced in two sequential enzymatic ATP-dependent reactions which occur exclusively in cytosol

Holst JJ, Albrechtsen NJW, Rosenkilde MM, Deacon CF

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AstraZeneca plc AstraZeneca is a British-Swedish multinational pharmaceutical company headquartered in Cambridge, United Kingdom