Although no specific definition is used in the literature for clinically significant WR, it can be defined as progressive weight gain after a successful initial weight loss [1]
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The outcomes from these studies suggest that Semaglutide GLP-1 can be an effective strategy for managing weight over the long run, particularly when combined with lifestyle modifications
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The FDA has only approved six weight loss drugs, including: Bupropion-naltrexone (Contrave) Liraglutide (Saxenda) Orlistat (Xenical, Alli) Phentermine-topiramate (Qsymia) Semaglutide (Wegovy) Setmelanotide (Imcivree) Currently, the choice of weight loss drugs remains very limited and is divided into two main categories: pancreatic lipase inhibitors and appetite suppressants that act on the central nervous system