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Properly stored lyophilized TB-500 is commonly stable for up to 24 months, depending on the manufacturer

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Despite minor variations depend on the specific NLRP involved, inflammasomes generally share a conserved structure comprising three main components: caspase-1, which processes pro-IL-1 and pro-IL-18 into their active forms

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Major exogenous causative factors are infections, intake of particular substances, and radiation, while endogenous factors are mainly sex and genetic disposition (Figure 1)

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