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[115] This functionality is lost in vitamin B 12 deficiency, resulting in an increased homocysteine level and the trapping of folate as 5-methyl-tetrahydrofolate, from which THF (the active form of folate) cannot be recovered

Ongoing surveillance is only recommended if extensive gastric atrophy, intestinal metaplasia, or additional risk factors are identified

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Lipo refers to fat, and tropic means to stimulate or enhance a particular function