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If your high B12 is from supplements or injections, stopping or reducing the dose will allow levels to return to normal over weeks to months

Human-specific data are sparse

A decrease in PLP has also been observed in the cerebrospinal fluid from ISOD and MocoD patients (39)

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By simultaneously activating GLP-1R to boost insulin secretion and GCGR to stimulate fat oxidation, these medications outperform single-target therapies in enhancing metabolism (Boland et al., 2020)

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