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Our findings in brain organoids with PSEN1 mutation complement well the results in human cortical organoids challenged with A that showed an increased expression of ferroptosis-promoting factors like Phkg243, Txnrd144 and Pparg42 [50]

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Frontiers in Endocrinology , 14, 1156123

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To test this hypothesis, trials of inhaled hyaluronic acid in individuals with AATD are under way in the hope of preventing the progression of this lung disease