We hope further studies shed more light on this complicated picture, he says
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Baseline thyroid function tests (TSH, free T4) and calcitonin levels may be considered, though routine calcitonin monitoring is debated among endocrinologists
Differential diagnosis: Hepatocellular necrosis resulting from direct toxicity may have a diffuse or lobular distribution but also may be accompanied by infarction
The MHRA SmPC advises that when tirzepatide is used with insulin or a sulfonylurea, a reduction in the dose of these medications should be considered to reduce the risk of hypoglycaemia