As shown in Figure 3, inhibitors of NF-B and/or Akt/GSK3 pathway such as 9-methylstreptimidone (Figure 3A), 8-hydroxy verrucarin A (Figure 3C) and chrysomycin A (which has been identified twice in the screening) (Figure 3D) were able to decrease H 2 S production (upper panel), although 8-hydroxy verrucarin A and chrysomycin A also affected cell viability (lower panel)
Before we consider how other radicals are derived from oxygen radicals, it is necessary to mention some normal physiological processes that lead to formation of oxygen radicals
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The sacrifice was at day 3, 5, 7, and 14