50 These studies yielded mixed results with the RCT amongst breast cancer patients demonstrating harm from ALC administration, 48 the RCT of ovarian and prostate cancer patients demonstrating benefit, 49 and the RCT amongst multiple myeloma patients demonstrating no significant difference between ALC and placebo
Both PAD and tTG are active in joints and the intestine, with the latter of these modification proteins being over expressed in the synovium of RA patients suggesting a possible role in disease pathogenesis (Lauzier et al
A systematic review that investigated the beneficial effects of L-Carnitine supplementation for weight management in overweight and obese adults found that L-Carnitine significantly reduced weight, BMI, and fat mass[2] 2
This transport process includes several steps ('carnitine shuttle'), which are described above for VPA [34, 35]
[5] Stephens FB, et al, 2006a: An acute increase in skeletal muscle carnitine content alters fuel metabolism in resting human skeletal muscle
254 YsebaertC.DenolP.WeynantsV.BakaletzL
