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Similar content being viewed by others 1 Introduction Peptide and protein therapeutics play an increasingly important role in the treatment of numerous diseases, but the development of oral peptide therapies remains an ongoing challenge [1,2,3,4]

The FDA has approved semaglutide under two brand names: Ozempic for type 2 diabetes management and Wegovy for chronic weight management

Both liver and cardiovascular diseases involve fibrotic processes

Rescue therapy with other glucose-lowering agents was allowed per protocol criteria

As melanin production returns to normal, they often lighten gradually rather than immediately

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