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We hypothesized that cerebrospinal fluid constituents at baseline would be significantly different between ME/CFS and controls and would correlate with symptoms such as fatigue, pain and quality of life (disability), semiobjective measures of central sensitization (dolorimetry) that may account for the tenderness and interoceptive complaints, and psychological constructs of disease

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Some people book one occasionally, when they're run down or recovering from a busy stretch

The key takeaway is that the wrong amount of bac water, whether too much or too little, will compromise the integrity of your experiment

2021;218(6):e20210518

Step 5: Reintroduce slowly, if at all