Future research should further explore the specific mechanisms of autophagy in osteoporosis associated with T2DM to provide a more solid scientific basis for clinical interventions ( Figure 4 )
ZZ: Conceptualization, Writing original draft, Visualization
Large, high-fat meals exacerbate nausea and early satiety caused by GLP-1-mediated gastric emptying delay
Numerous clinical trials, including rigorous randomized placebo-matched control studies, have all failed to show any positive clinical benefit for NSAIDs over placebo for the management of wide- spread pain associated with FMS.7 Even the corticosteroids such as prednisone show no better results than placebo when given to FMS patients.6 Based on these studies, it appears that gross soft-tissue inflammation does not play a major role in the pathogenesis of FMS
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