Yes, dietary fiber increases endogenous GLP-1 secretion through microbial fermentation in the colon, but the magnitude and duration of this effect varies significantly between individuals based on genetics, microbiota composition, and baseline metabolic markers
Moriya R, Shirakura T, Ito J, et al
References : [1] Johnson, S
In this study, we identified a metabolically dysfunctional subset of disease-associated CD38-expressing CD4 + T cells before symptom onset in AD which, when targeted in 5xFAD mice, resulted in an improvement of metabolic fitness and cognition
Baseline characteristics of the patients were compared using the 2 test, Fishers exact test, unpaired t test, or Wilcoxon rank-sum test, as appropriate
While this is exciting news, one potential side effect often raises concerns: muscle loss