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There are gastrointestinal conditions affecting absorption

[DOI] [PMC free article] [PubMed] [Google Scholar] References to other published versions of this review VidalAlaball 2005 VidalAlaball J, Butler CC, CanningsJohn R, Goringe A, Hood K, McCaddon A, et al

It is important to get enough vitamin B12 during pregnancy and when nursing, as a B12 deficiency Learn more: What is vitamin B12 deficiency

Consequently, people who follow vegetarian or vegan diets are at greater risk of insufficient intake, as are older adults, who are more likely to have reduced gastric acid production affecting B12 absorption

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Preclinical studies showed lipolytic and anti-lipogenic effects, but human trials failed to demonstrate significant weight-loss outcomes