Targeting B-Raf inhibitor resistant melanoma with novel cell penetrating peptide disrupters of PDE8A-C-Raf
Retatrutide is a novel triple receptor agonist peptide that targets the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R)
Triple Action Mechanism: Under investigation for its roles in collagen and elastin production, anti-inflammatory signaling, and antioxidant enzyme activation offering a unique tool for studying multi-target tissue restoration
We are grateful to the Laboratory Animal Center of the National Taiwan University College of Medicine and Taiwan Mouse Clinic, Academia Sinica and Taiwan Animal Consortium for technical support with pathology determination
GLP-1 receptor agonists also slow gastric emptying, reduce appetite through central nervous system pathways, and promote satiety, leading to reduced caloric intake and weight loss
Mfazo Hove