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26 Oxidative stress in the placenta, caused by an imbalance between oxidants and antioxidants such as vitamins A, C, and E, can contribute to first-trimester miscarriage

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The two act on separate receptors that converge on the same outcome

In addition, there is considerable evidence that estrogen increases substantially the activities of GPX and Glutamate Cysteine Ligase (GCL), an enzyme in the GSH pathway [5-7]

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