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Melanotan is normally self-administered through a tiny injection that cannot be felt

Hormonal factors may play a role because estrogen, progesterone, and testosterone have been shown to affect CSF secretion rates, potentially contributing to IIH development in individuals with obesity

Published skin studies typically use 12-week evaluation windows

Combining these two agents has opened new avenues for more comprehensive metabolic control, potentially improving weight loss outcomes and glycemic management beyond what either drug can achieve alone

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