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Specifically, it might be speculated that the interaction of IGF-1 analogs with their specific receptors might initiate a series of biochemical reactions via the PI3K pathway, posited as essential for cell proliferation and survival

Categorical data were described using frequencies and percentages, and differences between groups were analyzed using the chi-square test or Fishers exact test

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Results The mean weight loss among patients prescribed GLP-1 analogue monotherapy at 12 months was 11.42 kg, SD 9.95 (9.6% TBWL)