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Preservation of these spaces may facilitate regenerative cells and growth factors infiltration and more sustained exposure of biologic agents and their signaling mediators, thereby supporting tissue remodeling

Pellegrino M, Mancini F, Luc R, Coletti A, Giacch N, Manni I, et al

Nature 588 , 479484 (2020)

While the direct neuroprotective effects of blood flow restriction exercise remain unclear (Trpel et al., 2018), exercise of any form are suggested to have positive effects on brain function