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We have recently demonstrated that selective neuronal stimulation in the contralesional LCN using optogenetic approaches resulted in robust and persistent recovery after stroke, as stroke mice maintained their improved performance even after cessation of stimulation for 2 weeks [75]

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The tissue is identifiable, the injection can be placed in proximity, and BPC-157s direct activation of tendon fibroblasts and local angiogenesis addresses the biological bottleneck precisely

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In the SURMOUNT-1 trial, tirzepatide produced average weight loss of 15-22.5% of body weight over 72 weeks depending on dose

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