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Indeed, TOMM20 over-expression promotes cell proliferation and migration through enhanced ATP synthesis, whereas its downregulation impairs mitochondrial dysfunction (Park et al., 2019)

2 Mechanisms of OS-induced nerve damage In the context of DN, OS contributes to oxidase activation, mitochondrial dysfunction, apoptosis, inflammation, and endoplasmic reticulum (ER) stress, which are critical in the pathogenesis of nerve injury (Figure 1)

How Should Semaglutide be Administered

Exp Biol Med (Maywood)