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People with pre-existing IBS If you have irritable bowel syndrome, particularly the diarrhea-predominant subtype (IBS-D), retatrutide can exacerbate your existing condition significantly

The effect was functionally similar to a coverage removal, as the barriers to approval became high enough that many patients could not navigate the process successfully

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10.1186/s12902-024-01775-2 69 SommE.MontandonS