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Cancer Lett 48, 4351

However, as DPP4 recognizes other substrates such as chemokines, growth factors and neuropeptides, pleiotropic effects have been observed in patients treated with DPP4i

137139 THCV is an inverse agonist of the CB1 receptor, similar to Rimonabant

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The post says metformin requires adequate renal function, citing an eGFR typically at or above 30 to 45, and lists severe renal impairment as a contraindication along with acute illness and contrast dye procedures