Fernando Pea-Ortega, National Autonomous University of Mexico, Mexico Updates Copyright 2021 Andrade-Talavera and Rodrguez-Moreno
Furthermore, recent studies have demonstrated that Zn supplementation provides some benefits to people with obesity (with and without diabetes) by enhancing insulin sensitivity and reducing inflammation and oxidative stress (by increasing MT expression), which leads to the attenuation of the destructive effect of obesity on the liver, heart, and kidneys [81]
Hence, patients should undergo TPMT genotype testing before starting thiopurine therapy
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While some have faded into obscurity, others have stood the test of time due to their proven benefits and effectiveness