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This review offers an evidence-informed framework for orthopaedic surgeons seeking to navigate the evolving field of therapeutic peptides

This effect has been previously demonstrated in an infant rat model of pneumococcal meningitis 17 and in whole blood cultures from human patients with acute COVID-19 18

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The barrier breakdown also allows the intestinal microbiota and its derivatives (e.g., lipopolysaccharides (LPS)) to penetrate the epithelial barrier, which triggers innate and adaptive immune signaling pathways 68

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These improvements matched lower serum levels of BNP and NT-proBNP, which tell us how severe heart failure is [15]