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Diabetes mellitus as a risk factor for depression

35 , e21212 (2021)

Clinical investigations suggest that the cerebrospinal fluid (CSF) levels of HMGB1 in patients with subarachnoid hemorrhage (SAH) demonstrate a positive correlation with proinflammatory factors, such as IL6 and TNF, and that the degree of HMGB1 elevation is closely related to the severity of the disease [353]