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Because peptide stability, delivery method, and study design vary considerably across the literature, direct comparisons between studies should be made cautiously

J Clin Oncol 41:373384

Life Sci 272:119241 Hassanein EH, Shalkami A-GS, Khalaf MM, Mohamed WR, Hemeida RA (2019) The impact of Keap1/Nrf2, P38MAPK/NF-B and Bax/Bcl2/caspase-3 signaling pathways in the protective effects of berberine against methotrexate-induced nephrotoxicity

So for chronic degenerative conditions, my bias is to avoid it, and my bias strengthens the longer someone wants to use it

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