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Based on the exclusion criteria, 19 were excluded due to comorbidity (nine HC and three PD), contraindication to MRI (two HC and three PD), and due to cognitive impairment (two HC)

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Its GLP-1 market, valued at about $1.7 billion in 2023 according to Clarivate, is expected to grow as the number of obesity patients is projected to exceed 500 million by 2033

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The functional relevance of these changes has been highlighted by interventional studies in which sodium butyrate supplementation (200 mg/kg/day) in diabetic C57BL mice with 14-day quercetin pretreatment restored colonic tight junction expression and decreased circulating lipopolysaccharide levels by 42% (26)

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