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In contrast to the livers with low mitochondrial NAD + , the livers from the mice overexpressing SLC25A51 regenerated significantly better than those of the enhanced green fluorescent protein (eGFP)-expressing controls (Fig

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The changes in transcriptional factors of signaling pathways, and inflammations were assessed in those cells

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In summary, pyroptosis is closely linked to PD pathogenesis by driving neuroinflammation, and its interaction with apoptotic pathways may further accelerate disease progression