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O-GlcNAc modification of PPAR reduces its transcriptional activity

After further culturing for 24 h, each well was washed, 1 mg mL 1 MTT solution (100 L) was added, and the cells were re-incubated for 4 h in the dark

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Unhealthy Diets Diets high in sugar and unhealthy fats, such as trans fats and saturated fats, can negatively impact brain function by inducing inflammation, oxidative stress, and insulin resistance, all of which disrupt neuronal health and cognitive processes