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For those with severe deficiencies, B12 injections may be an option to restore levels effectively

Abstract Cerebrovascular diseases, including ischemic stroke and vascular cognitive impairment, represent a significant global health challenge due to the paucity of effective treatment options

Meta-analysis of randomized controlled trials shows a 28% reduction in myocardial infarction risk and meaningful reductions in both systolic and diastolic blood pressure ^15

GLP-1 receptor agonists: fighting obesity with an eye to cardiovascular risk

These central pathways should therefore be regarded as biologically plausible but pharmacologically speculative in the clinical context, pending direct evidence of sufficient CNS target engagement