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Glutathione plays a crucial role in protecting cells from oxidative stress, which is implicated in the pathogenesis of many diseases, including neurodegenerative disorders, cardiovascular diseases, and liver diseases

Jacovina and colleagues reported a unique in vivo mechanism suggesting that an annexin A2-deficient mouse rendered hyperhomocysteinemic by dietary means demonstrated impaired fibrinolysis, perivascular fibrin persistence, and attenuated angiogenesis (angiostasis) (4)

HOMA-IR estimates insulin resistance and is good for fertility risk stratification

GHK-Cu acts as a signaling molecule

These findings propose a paradigm that places neutrophil ferroptosis at the center of the pathogenesis of SLE