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Your diet, nutritional profile, liver health, stress levels, and the amount of sleep you get each night all play a part

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Journal of clinical pharmacy and therapeutics 37, 13 (2012)

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Am J Physiol 280:C415422 Myllyharju J, Koivunen P (2013) Hypoxia-inducible factor prolyl 4-hydroxylases: common and specific roles

This means every dose goes where it is needed most, ensuring optimal concentrations of the active substance in the bloodstream