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Description

The 1 g / 100 mL solution for infusion contains 15.2 mmol (or 350 mg) sodium per 100 mL bag and the 2.5 g / 250 mL solution for infusion contains 38 mmol (or 875 mg) sodium per bag of 250 ml

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The four groups of nude mice then received different treatments: one group received si-PGC-1 LNP, another received an equal dose of LNP, and the third and fourth groups received si-PGC-1 alone or PBS solution

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In certain instances, once exposure to an active agent (e.g., concentration in the endolymph or perilymph) reaches steady state, the concentration of an active agent in the endolymph or perilymph stays at or about the therapeutic dose for an extended period of time (e.g., one day, 2 days, 3 days, 4 days, 5 days, 6 days, 1 week, 3 weeks, 6 weeks, or 2 months)

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